Substituted phenylmorpholines, or substituted phenmetrazines alternatively, are chemical derivatives of 2-phenylmorpholine or of the psychostimulant drug phenmetrazine.

Most such compounds act as releasers of monoamine neurotransmitters, and have stimulant effects. Some also act as agonists at serotonin receptors, and compounds with an N-propyl substitution act as dopamine receptor agonists.

A number of derivatives from this class have been investigated for medical applications, such as for use as anorectics or medications for the treatment of ADHD. Some compounds have also become subject to illicit use as designer drugs.

List of phenylmorpholines

Additional phenylmorpholines and their activities as monoamine releasing agents (MRAs) have been described.

See also

  • Substituted amphetamine
  • Substituted benzofuran
  • Substituted cathinone
  • Substituted methylenedioxyphenethylamine
  • List of aminorex analogues
  • List of methylphenidate analogues
  • List of phenyltropanes
  • List of cocaine analogues

References

External links

  • Media related to Substituted phenylmorpholines at Wikimedia Commons

Substituted phenylmorpholine Wikipedia

Proposed mechanisms for reactions between para substituted phenols

Phenylephrin vs. Pseudoephedrin Was ist der Unterschied zwischen den

Elektrophile Substitution Die Zweitsubstitution

Substituted Phenylmorpholine Vesicular Monoamine Transporter 1